Two variable active site residues modulate response regulator phosphoryl group stability
نویسندگان
چکیده
منابع مشابه
The Mechanism of Phosphoryl Transfer Reaction and the Role of Active Site Residues on the Basis of Ribokinase-Like Kinases
The role of ribokinase-like carbohydrate kinases consists in ATP dependent phosphorylation of small molecules containing hydroxymethyl group. Although they differ substantially in structural terms and exhibit a broad substrate specificity, some family-wide conserved features can be distinguished suggesting the common mode of action. 4-methyl-5-hydroxyethylthiazole kinase (Thz kinase) was chose...
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ژورنال
عنوان ژورنال: Molecular Microbiology
سال: 2008
ISSN: 0950-382X,1365-2958
DOI: 10.1111/j.1365-2958.2008.06296.x